The Best Fluoride-Free Toothpaste of 2025

Will big toothpaste clap back after this study?

It took two and a half years, multiple formulations, a research partnership, and full product transparency to get to this point…

But here at biom, we finally have what most “natural” oral care brands don’t:

A peer-reviewed study on our actual formula.

No, it’s not a white paper.

And it’s not a dusty old claim recycled from some generic ingredient supplier.

That’s right: we had the full NOBS Toothpaste Tablet tested against fluoride under conditions meant to simulate actual tooth decay.

What fluoride toothpaste?

Well…I have decorum, so I’ll just say it’s the #1 toothpaste in America.

And we beat it.

The study was neither pretty nor gentle.

In fact, it was basically a cavity-from-h*ll simulator.

Think the kind of environment that takes people from minor sensitivity to major dental bills.

We tested a bunch of different things, so you should read the full study. I’ll make it clear though:

After seven days, teeth brushed with NOBS had half the enamel damage compared to no brushing.

And here's the kicker: it protected just as well as fluoride toothpaste, without any fluoride.

“Fluoride is the gold-standard”, they said.

“You can’t heal teeth without fluoride”, they said.

They were wrong.

You knew it, and we knew it. But now, the whole damn world is going to know it too.

If you’re with us in building a healthier world, you’re in good company.

This is just the beginning.

Thank you for being here with us.

Cheers,

Fawn